UPDATE 2014-02-10: Check out my free/PWYW downloadable resources for Autodesk Sketchbook Pro: the grid I use, the brushes, and a PSD that has the grid and a blank layer.
Matt just got a tablet, so he wanted to know how I set up Autodesk Sketchbook Pro for my sketchnoting. See the sketchnote below for my layout and brush sizes, and a few other tips. =) I sometimes tweak brush sizes depending on the size of the project, but they’re roughly around that proportion (1.1-1.3, 2.3-2.5, 4.6 or so).
The dot grid I use works out to roughly 40 pixels square with dots that are 5 pixels or so in diameter. If I draw small letters at 1 grid unit (~40px) high, this is mostly readable when printed on 8.5”x11” and requires a little scrolling and zooming when viewing on the computer. I usually draw titles at 2-3 grid units high (80 or 120 pixels). Sometimes I use the dot grid just as a guide for keeping letters mostly level, and I pick a size in between.